Publications
(*Corresponding)
62. Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
Zhang, L. J.;* Elsallabi, O.; Soto-Palma, C.; Bartz, J.; Salekeen, R.; Nunes, A.; Xu, W.; Lee, K.; Hughes, B.; Zhang, B.; Mohamed, A.; Mcgowan, S.; Angelini, L.; O'Kelly, R.; Biashad, S. A.; Hillpot, E.; Morandini, F.; Seluanov, A.; Gorbunova, V.; Dong, X.; Niedernhofer, L. J.; Robbins, P. D.*
bioRxiv 2025.04.27.650852.
https://doi.org/10.1101/2025.04.27.650852
61. SIRT6 activator fucoidan extends healthspan and lifespan in aged wild-type mice
Biashad, S. A.; Hillpot, E.; Morandini, F.; Rechsteiner, C.; Paige, V.; Tombline, G.; Lee, M.; Zheng, Z.; Liang, Y.; Martinez, J.; Sieczkiewicz, N.; Zhang, Z.; Volobaev, V.; Firsanov, D.; Simon, M.; Zhang, L. J.; Robbins, P. D.; Seluanov, A.; Gorbunova, V.
bioRxiv 2025, 2025.03.24.645072.
https://doi.org/10.1101/2025.03.24.645072
60. The fifth annual symposium of the Midwest Aging Consortium
Reader, B. F.; Rosas, L.; Knopf, B. A.; Liu, Y.; Alzate-Correa, D.; Bhat, A.; Carey, A.; Cuervo, A. M.; Dayal, S.; Demarco, R. S.; Elliehausen, C. J.; Englund, D. A.; Hamilton, H. L.; Johnston, M.; Kang, P.; Konopka, A. R.; Lepola, N.; Presley, C. J.; Schafer, M. J.; Serrano, J.; Singer, B. D.; Song, M. A.; Stanford, K. I.; Taylor, J.; Wei, W.; Yeh, C. Y.; Zhang, L.; Zhang, L.; Anderson, R. M.; Bai, H.; Robbins, P. D.; Lamming, D. W.; Mihaylova, M. M.; Rojas, M.; Mora, A. L.
J. Gerontol. A. Biol. Sci. Med. Sci. 2025, 80(2), glae296.
https://doi.org/10.1093/gerona/glae296
59. Development of novel flavonoid senolytics through phenotypic drug screening and drug design
Zhang, L. J.;* Salekeen, R.; Soto-Palma, C.; He, Y.; Elsallabi, O.; Hughes, B.; Nunes, A.; Xu, W.; Zhang, B.; Mohamed, A.; McGowan, S. J.; Angelini, L.; O’Kelly, R.; Kamenecka, T. M.; Niedernhofer, L. J.; Robbins, P. D.*
bioRxiv 2024, 2024.10.27.620529.
https://doi.org/10.1101/2024.10.27.620529
58. Identification of lipid senolytics targeting senescent cells through ferroptosis induction
Zhang, L. J.;* Salekeen, R.; Soto-Palma, C.; Elsallabi, O.; Ye, H.; Hughes, B.; Zhang, B.; Nunes, A.; Lee, K.; Xu, W.; Mohamed, A.; Piepgras, E.; McGowan, S. J.; Angelini, L.; O'Kelly, R.; Han, X.; Niedernhofer, L. J.; Robbins, P. D.*
bioRxiv 2024, 2024.10.14.618023.
https://doi.org/10.1101/2024.10.14.618023
57. Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia
Englund, D. A.; Jolliffe, A. M.; Hanson, G. J.; Aversa, Z.; Zhang, X.; Jiang, X.; White, T. A.; Zhang, L.; Monroe, D. G.; Robbins, P. D.; Niedernhofer, L. J.; Kamenecka, T. M.; Khosla, S.; LeBrasseur, N. K.
JCI Insight 2024, 9(2), e169512.
https://doi.org/10.1172/jci.insight.169512
56. Targeting cellular senescence with senotherapeutics: senolytics and senomorphics
Zhang, L.; Pitcher, L. E.; Prahalad, V.; Niedernhofer, L. J.; Robbins, P. D.
FEBS J. 2023, 290(5), 1362.
https://doi.org/10.1111/febs.16350
55. Longevity-associated SMAD3 non-coding centenarian variant impairs a cell-type specific enhancer to reduce inflammation
Yang, J.; Tare, A.; Zhang, L.; Kim, S.; Ryu, S.; Guo, Q.; Zhu, Y.; Wang, X.; Wang, X.; Hudgins, A.; Guan, D.; Jin, C.; Chang, H.-K.; Atzmon, G.; Milman, S.; Barzilai, N.; Vijg, J.; Niedernhofer, L.; Robbins, P. D.; Suh, Y.
bioRxiv 2023, 2023.05.17.540984.
https://doi.org/10.1101/2023.05.17.540984
54. In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
Samakkarnthai, P.; Saul, D.; Zhang, L.; Aversa, Z.; Doolittle, M. L.; Sfeir, J. G.; Kaur, J.; Atkinson, E. J.; Edwards, J. R.; Russell, G. G.; Pignolo, R. J.; Kirkland, J. L.; Tchkonia, T.; Niedernhofer, L. J.; Monroe, D. G.; Lebrasseur, N. K.; Farr, J. N.; Robbins, P. D.; Khosla, S.
Aging 2023, 15(9), 3331.
https://doi.org/10.18632/aging.204701
bioRxiv 2023, 2023.02.23.529777.
https://doi.org/10.1101/2023.02.23.529777
53. Challenges in developing Geroscience trials
Rolland, Y.; Sierra, F.; Ferrucci, L.; Barzilai, N.; De Cabo, R.; Mannick, J.; Oliva, A.; Evans, W.; Angioni, D.; De Souto Barreto, P.; Raffin, J.; Vellas, B.; Kirkland, J. L.; group, G. C. T. T.
Nat. Commun. 2023, 14(1), 5038.
https://doi.org/10.1038/s41467-023-39786-7
52. Cellular senescence: a key therapeutic target in aging and diseases
Zhang, L.; Pitcher, L. E.; Yousefzadeh, M. J.; Niedernhofer, L. J.; Robbins, P. D.; Zhu, Y.
J. Clin. Invest. 2022, 132(15), e158450.
https://doi.org/10.1172/JCI158450
51. Fucoidans are novel senotherapeutics that enhance Sirt6 and DNA repair activity
Zhang, L.; Hughes, B.; Tombline, G.; Angelini, L.; Yousefzadeh, M.; Gorbunova, V.; Niedernhofer, L. J.; Robbins, P. D.
Innovation in Aging 2022, 6(S1), 130.
https://doi.org/10.1093/geroni/igac059.522
50. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Simon, M.; Yang, J.; Gigas, J.; Earley, E. J.; Hillpot, E.; Zhang, L.; Zagorulya, M.; Tombline, G.; Gilbert, M.; Yuen, S. L.; Pope, A.; Van Meter, M.; Emmrich, S.; Firsanov, D.; Athreya, A.; Biashad, S. A.; Han, J.; Ryu, S.; Tare, A.; Zhu, Y.; Hudgins, A.; Atzmon, G.; Barzilai, N.; Wolfe, A.; Moody, K.; Garcia, B. A.; Thomas, D. D.; Robbins, P. D.; Vijg, J.; Seluanov, A.; Suh, Y.; Gorbunova, V.
EMBO J 2022, 41(21), e110393.
https://doi.org/10.15252/embj.2021110393
bioRxiv 2021, 2021.12.13.472381.
https://doi.org/10.1101/2021.12.13.472381
49. Novel small molecule inhibition of IKK/NF-kB activation reduces markers of senescence and improves healthspan in mouse models of aging
Zhang, L.; Zhao, J.; Mu, X.; McGowan, S. J.; Angelini, L.; O'Kelly, R. D.; Yousefzadeh, M. J.; Sakamoto, A.; Aversa, Z.; LeBrasseur, N. K.; Suh, Y.; Huard, J.; Kamenecka, T. M.; Niedernhofer, L. J.; Robbins, P. D.
Aging Cell 2021, 20(12), e13486.
https://doi.org/10.1111/acel.13486
48. Recent advances in the discovery of senolytics
Zhang, L.; Pitcher, L. E.; Prahalad, V.; Niedernhofer, L. J.; Robbins, P. D.
Mech. Ageing Dev. 2021, 200, 111587.
https://doi.org/10.1016/j.mad.2021.111587
47. Targeting cellular senescence with novel senotherapeutics by design to extend healthspan
Zhang, L.; Hughes, B.; Angelini, L.; O’Kelly, R.; Yousefzadeh, M.; Kamenecka, T.; Niedernhofer, L.; Robbins, P.
Innovation in Aging 2021, 5 (S1), 681.
https://doi.org/10.1093/geroni/igab046.2564
46. Senolytics reduce coronavirus-related mortality in old mice
Camell, C. D.; Yousefzadeh, M. J.; Zhu, Y.; Prata, L.; Huggins, M. A.; Pierson, M.; Zhang, L.; O'Kelly, R. D.; Pirtskhalava, T.; Xun, P.; Ejima, K.; Xue, A.; Tripathi, U.; Espindola-Netto, J. M.; Giorgadze, N.; Atkinson, E. J.; Inman, C. L.; Johnson, K. O.; Cholensky, S. H.; Carlson, T. W.; LeBrasseur, N. K.; Khosla, S.; O'Sullivan, M. G.; Allison, D. B.; Jameson, S. C.; Meves, A.; Li, M.; Prakash, Y. S.; Chiarella, S. E.; Hamilton, S. E.; Tchkonia, T.; Niedernhofer, L. J.; Kirkland, J. L.; Robbins, P. D.
Science 2021, 373(6552), eabe4832.
https://www.doi.org/10.1126/science.abe4832
45. ATM is a key driver of NF-kB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging
Zhao, J.;# Zhang, L.;# (#Co-first author) Lu, A.; Han, Y.; Colangelo, D.; Bukata, C.; Scibetta, A.; Yousefzadeh, M. J.; Li, X.; Gurkar, A. U.; McGowan, S. J.; Angelini, L.; O'Kelly, R.; Li, H.; Corbo, L.; Sano, T.; Nick, H.; Pola, E.; Pilla, S. P. S.; Ladiges, W. C.; Vo, N.; Huard, J.; Niedernhofer, L. J.; Robbins, P. D.
Aging 2020, 12(6), 4688.
https://doi.org/10.18632/aging.102863
44. Attenuation of ataxia telangiectasia mutated signaling mitigates age-associated intervertebral disc degeneration
Han, Y.; Zhou, C. M.; Shen, H.; Tan, J.; Dong, Q.; Zhang, L.; McGowan, S. J.; Zhao, J.; Sowa, G. A.; Kang, J. D.; Niedernhofer, L. J.; Robbins, P. D.; Vo, N. N.
Aging Cell 2020, 19(7), e13162.
https://doi.org/10.1111/acel.13162
43. ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, G. V.; Abdelmohsen, K.; Andreux, P.; Bagdonaite, I.; Barzilai, N.; Brunak, S.; Cabreiro, F.; de Cabo, R.; Campisi, J.; Cuervo, A. M.; Demaria, M.; Ewald, C. Y.; Fang, E. F.; Faragher, R.; Ferrucci, L.; Freund, A.; Silva-Garcia, C. G.; Georgievskaya, A.; Gladyshev, V. N.; Glass, D. J.; Gorbunova, V.; de Grey, A.; He, W. W.; Hoeijmakers, J.; Hoffmann, E.; Horvath, S.; Houtkooper, R. H.; Jensen, M. K.; Jensen, M. B.; Kane, A.; Kassem, M.; de Keizer, P.; Kennedy, B.; Karsenty, G.; Lamming, D. W.; Lee, K. F.; MacAulay, N.; Mamoshina, P.; Mellon, J.; Molenaars, M.; Moskalev, A.; Mund, A.; Niedernhofer, L.; Osborne, B.; Pak, H. H.; Parkhitko, A.; Raimundo, N.; Rando, T. A.; Rasmussen, L. J.; Reis, C.; Riedel, C. G.; Franco-Romero, A.; Schumacher, B.; Sinclair, D. A.; Suh, Y.; Taub, P. R.; Toiber, D.; Treebak, J. T.; Valenzano, D. R.; Verdin, E.; Vijg, J.; Young, S.; Zhang, L.; Bakula, D.; Zhavoronkov, A.; Scheibye-Knudsen, M.
Aging 2020, 12(24), 24484.
https://doi.org/10.18632/aging.202454
42. Methods to quantify the NF-κB pathway during senescence
Zhang, L.; Zhao, J.; Gurkar, A.; Niedernhofer, L. J.; Robbins, P. D.
In Cellular Senescence: Methods and Protocols, Demaria, M., Ed. Springer New York: New York, NY, 2019; pp 231.
https://doi.org/10.1007/978-1-4939-8931-7_18
41. Signal transduction, ageing and disease
Zhang, L.; Yousefzadeh, M. J.; Suh, Y.; Niedernhofer, L. J.; Robbins, P. D.
In Biochemistry and Cell Biology of Ageing: Part II Clinical Science, Harris, J. R.; Korolchuk, V. I., Eds. Springer: Singapore, 2019; pp 227.
https://doi.org/10.1007/978-981-13-3681-2_9
40. Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice
Flores, R. R.; Carbo, L.; Kim, E.; Van Meter, M.; De Padilla, C. M. L.; Zhao, J.; Colangelo, D.; Yousefzadeh, M. J.; Angelini, L. A.; Zhang, L.; Pola, E.; Vo, N.; Evans, C. H.; Gambotto, A.; Niedernhofer, L. J.; Robbins, P. D.
FASEB J. 2019, 33(8), 9505.
https://doi.org/10.1096/fj.201900420R
39. Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-kB activation
Zhao, J.; Zhang, L.; Mu, X.; Doebelin, C.; Nguyen, W.; Wallace, C.; Reay, D. P.; McGowan, S. J.; Corbo, L.; Clemens, P. R.; Wilson, G. M.; Watkins, S. C.; Solt, L. A.; Cameron, M. D.; Huard, J.; Niedernhofer, L. J.; Kamenecka, T. M.; Robbins, P. D.
PLoS Biol. 2018, 16(6), e2004663.
https://doi.org/10.1371/journal.pbio.2004663
38. Discovery of novel small-molecule inhibitors of NF-kB signaling with antiinflammatory and anticancer properties
Zhang, L.; Shi, L.; Soars, S. M.; Kamps, J.; Yin, H.
J. Med. Chem. 2018, 61(14), 5881.
https://doi.org/10.1021/acs.jmedchem.7b01557
37. Discovery of small molecules as multi-Toll-like receptor agonists with proinflammatory and anticancer activities
Zhang, L.; Dewan, V.; Yin, H.
J. Med. Chem. 2017, 60(12), 5029.
https://doi.org/10.1021/acs.jmedchem.7b00419
Graduate Work:
36. [Diversity-oriented synthesis and its application in drug discovery]
Zhang, L.; Zheng, M. Y.; Liu, H.
Acta pharmaceutica Sinica. 2015, 50(4), 419
35. Palladium-catalyzed difunctionalization of alkynes via C-N and S-N cleavages: a versatile approach to highly functional indoles
Zhao, F.; Zhang, D.; Nian, Y.; Zhang, L.; Yang, W.; Liu, H.
Org. Lett. 2014, 16(19), 5124
34. Rapid generation of privileged substructure-based compound libraries with structural diversity and drug-likeness
Zhang, L.; Zheng, M.; Zhao, F.; Zhai, Y.; Liu, H.
ACS Comb. Sci. 2014, 16(4), 184
33. [Bioisosteric replacement and its application in drug design]
Zhang, L.; Liu, H.
Chin. J. Med. Chem. 2014, 24(3), 214
32. One-pot metal-free synthesis of highly substituted pyrroles from 2-acetyl-3-methylene-1,4-dicarbonyl compounds and primary amines via TBHP and activated carbon oxidative aromatization of dihydropyrrole
Yang, W.; Zhou, Y.; Sun, H.; Zhang, L.; Zhao, F.; Liu, H.
RSC Adv. 2014, 4(29), 15007
31. (R)-3-amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one derivatives as potent inhibitors of dipeptidyl peptidase-4: design, synthesis, biological evaluation, and molecular modeling
Wang, S.; Su, M.; Wang, J.; Li, Z.; Zhang, L.; Ji, X.; Li, J.; Li, J.; Liu, H.
Bioorg. Med. Chem. 2014, 22(23), 6684
30. A simple copper-catalyzed two-step one-pot synthesis of indolo[1,2-a]quinazoline
Li, C.; Zhang, L.; Shu, S.; Liu, H.
Beilstein J. Org. Chem. 2014, 10, 2441
29. Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
Ji, X.; Xia, C.; Wang, J.; Su, M.; Zhang, L.; Dong, T.; Li, Z.; Wan, X.; Li, J.; Li, J.; Zhao, L.; Gao, Z.; Jiang, H.; Liu, H.
Eur. J. Med. Chem. 2014, 86, 242
28. [Application of efficient synthetic techniques in drug research]
Zhou, Y.; Zhang, L.; Li, Z.; Liu, H.
Acta pharmaceutica Sinica. 2013, 48(7), 1014
27. Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives through copper-catalyzed intramolecular N-arylation
Zhao, F.; Zhang, L.; Liu, H.; Zhou, S.; Liu, H.
Beilstein J. Org. Chem. 2013, 9, 2463
26. Selective synthesis of 5,6‐dihydroindolo[1,2‐a]quinoxalines and 6,7‐dihydroindolo[2,3‐c]quinolines by orthogonal copper and palladium catalysis
Zhang, L.; Zhao, F.; Zheng, M.; Zhai, Y.; Wang, J.; Liu, H.
Eur. J. Org. Chem. 2013, 2013(25), 5710
25. Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating
Zhang, L.; Zhao, F.; Zheng, M.; Zhai, Y.; Liu, H.
Chem. Commun. 2013, 49(28), 2894
24. Design, synthesis, structure-activity relationships, and docking studies of 1-(gamma-1,2,3-triazol substituted prolyl)-(S)-3,3-difluoropyrrolidines as a novel series of potent and selective dipeptidyl peptidase-4 inhibitors
Zhang, L.; Su, M.; Li, J.; Ji, X.; Wang, J.; Li, Z.; Li, J.; Liu, H.
Chem. Biol. Drug Des. 2013, 81(2), 198
23. Asymmetric Michael addition of N-tert-butanesulfinyl imidate with alpha,beta-unsaturated diesters: scope and application to the synthesis of indanone derivatives
Wang, J.; Zhou, Y.; Zhang, L.; Li, Z.; Chen, X.; Liu, H.
Org. Lett. 2013, 15(7), 1508
22. Three‐step one‐pot synthesis of 1,4‐dihydropyrazolo[4,3‐b]indoles using copper catalysis
Liu, H.; Zhang, L.; Zhao, F.; Liu, H.
Eur. J. Org. Chem. 2013, 2014(5), 1047
21. Gold(I)-catalyzed cascade approach for the synthesis of tryptamine-based polycyclic privileged scaffolds as alpha1-adrenergic receptor antagonists
Li, Z.; Li, J.; Yang, N.; Chen, Y.; Zhou, Y.; Ji, X.; Zhang, L.; Wang, J.; Xie, X.; Liu, H.
J Org Chem 2013, 78(21), 10802
20. [Application of phosphates and phosphonates prodrugs in drug research and development]
Ji, X.; Wang, J.; Zhang, L.; Zhao, L. X.; Jiang, H. L.; Liu, H.
Acta pharmaceutica Sinica. 2013, 48(5), 621
19. Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase
Zhang, L.; Chen, X.; Liu, J.; Zhu, Q.; Leng, Y.; Luo, X.; Jiang, H.; Liu, H.
Eur. J. Med. Chem. 2012, 58(Supplement C), 624
18. An expedient Pd/DBU mediated cyanation of aryl/heteroaryl bromides with K4[Fe(CN)6]
Zhang, D.; Sun, H.; Zhang, L.; Zhou, Y.; Li, C.; Jiang, H.; Chen, K.; Liu, H.
Chem. Commun. 2012, 48(23), 2909
17. Microwave-assisted one-step synthesis of acetophenones via palladium-catalyzed regioselective arylation of vinyloxytrimethylsilane
Qian, W.; Zhang, L.; Sun, H.; Jiang, H.; Liu, H.
Adv. Synth. Catal. 2012, 354(17), 3231
16. Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: selective inhibitors of dopamine D(1) receptor
Qian, W.; Lu, W.; Sun, H.; Li, Z.; Zhu, L.; Zhao, R.; Zhang, L.; Zhou, S.; Zhou, Y.; Jiang, H.; Zhen, X.; Liu, H.
Bioorg. Med. Chem. 2012, 20(15), 4862
15. Gold-catalyzed tandem reaction in water: an efficient and convenient synthesis of fused polycyclic indoles
Feng, E.; Zhou, Y.; Zhao, F.; Chen, X.; Zhang, L.; Jiang, H.; Liu, H.
Green Chem. 2012, 14(7), 1888
14. Synthesis of 2-phenylnaphthalenes through gold-catalyzed dimerization via a highly selective carbon nucleophile pathway
Wang, S.; Zhang, L.; Ding, X.; Zhou, Y.; Wang, J.; Jiang, H.; Liu, H.
J. Org. Chem. 2011, 76(11), 4514
13. Application of nickel(II) complexes to the efficient synthesis of alpha- or beta-amino acids
Wang, J.; Zhang, L.; Jiang, H.; Chen, K.; Liu, H.
Chimia (Aarau) 2011, 65(12), 919
12. Synthesis of 4‐aryl‐2(5H)‐furanones by gold(I)‐catalyzed intramolecular annulation
Sun, H.; Huang, H.; Zhang, D.; Feng, E.; Qian, W.; Zhang, L.; Chen, K.; Liu, H.
Adv. Synth. Catal. 2011, 353(9), 1413
11. Synthesis of Pyrrolo[1,2-a]quinoxalines via gold(I)-mediated cascade reactions
Liu, G.; Zhou, Y.; Lin, D.; Wang, J.; Zhang, L.; Jiang, H.; Liu, H.
ACS Comb. Sci. 2011, 13(3), 209
10. Microwave dielectric heating in modern organic synthesis and drug discovery
Liu, H; Zhang, L.
In Microwave Heating, Chandra, U., Ed. InTech: Rijeka, 2011; p Ch. 16.
9. Regioselective synthesis of 3-benzazepinones and unexpected 5-bromo-3-benzazepinones
Zhang, L.; Ye, D.; Zhou, Y.; Liu, G.; Feng, E.; Jiang, H.; Liu, H.
J. Org. Chem. 2010, 75(11), 3671
8. Novel therapeutics based on inhibiting the interaction of glycogen phosphorylase and GL-subunit of glycogen-associated protein phosphatase 1: WO2009127723
Zhang, L.; Liu, H.
Expert Opin. Ther. Pat. 2010, 20(7), 969
7. Most efficient routes for the synthesis of alpha,beta-diamino acid-derived compounds
Wang, J.; Zhang, L.; Jiang, H.; Liu, H.
Curr. Pharm. Des. 2010, 16(10), 1252
6. Highly enantio- and diastereoselective mannich reaction of a chiral nickel(ii) glycinate with an α-imino ester for asymmetric synthesis of a 3-aminoaspartate
Liu, H.; Wang, J.; Lin, D.; Shi, J.; Ding, X.; Zhang, L.; Jiang, H.
Synthesis 2010, 2010(07), 1205
5. Silver- and gold-mediated intramolecular cyclization to substituted tetracyclic isoquinolizinium hexafluorostilbates
Liu, F.; Ding, X.; Zhang, L.; Zhou, Y.; Zhao, L.; Jiang, H.; Liu, H.
J. Org. Chem. 2010, 75(17), 5810
4. Total Synthesis of Cytosporone B
Huang, H.; Zhang, L.; Zhang, X.; Ji, X.; Ding, X.; Shen, X.; Jiang, H.; Liu, H.
Chin. J. Chem. 2010, 28(6), 1041
3. Gold(I)-catalyzed tandem transformation: a simple approach for the synthesis of pyrrolo/pyrido[2,1-a][1,3]benzoxazinones and pyrrolo/pyrido[2,1-a]quinazolinones
Feng, E.; Zhou, Y.; Zhang, D.; Zhang, L.; Sun, H.; Jiang, H.; Liu, H.
J. Org. Chem. 2010, 75(10), 3274
2. Gold‐ and silver‐catalyzed intramolecular hydroamination of terminal alkynes: water‐triggered chemo‐ and regioselective synthesis of fused tricyclic xanthines
Ye, D.; Zhang, X.; Zhou, Y.; Zhang, D.; Zhang, L.; Wang, H.; Jiang, H.; Liu, H.
Adv. Synth. Catal. 2009, 351(17), 2770
1. Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase
Zhang, L.; Li, H.; Zhu, Q.; Liu, J.; Chen, L.; Leng, Y.; Jiang, H.; Liu, H.
Bioorg. Med. Chem. 2009, 17(20), 7301